Goal
Estimate adult creatinine clearance with the Cockcroft–Gault equation while clearly separating it from eGFR and medication-dosing decisions.
Cockcroft–Gault Creatinine Clearance Calculator
Estimate adult creatinine clearance with the Cockcroft–Gault equation while clearly separating it from eGFR and medication-dosing decisions.
Key facts
- What it does
- Estimate adult creatinine clearance with the Cockcroft–Gault equation while clearly separating it from eGFR and medication-dosing decisions.
- Formula
Cockcroft–Gault CrCl (mL/min) = [(140 − age) × weight (kg) × sex factor] ÷ [72 × serum creatinine (mg/dL)], using 0.85 for the female factor in the traditional equation.- You enter
- Sex factor used by the equation · Age · Body weight used · Serum creatinine
- Worked example
- CrCl = ((140 − 50) × 70) ÷ (72 × 1) = 87.5 mL/min.
A clearer path to an answer
From your question to a useful result
This page keeps the calculation transparent: define the goal, enter the matching values, inspect the method, and decide what the result means in your situation.
Inputs
Sex factor used by the equation · Age · Body weight used · Serum creatinine
Method
Cockcroft–Gault CrCl (mL/min) = [(140 − age) × weight (kg) × sex factor] ÷ [72 × serum creatinine (mg/dL)], using 0.85 for the female factor in the traditional equation.
Next step
Calculate, review the assumptions below, then compare a related tool when the decision needs more context.
Cockcroft–Gault Creatinine Clearance Calculator
Estimate adult creatinine clearance with the Cockcroft–Gault equation while clearly separating it from eGFR and medication-dosing decisions.
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Result
Enter your values above and choose Calculate to see the result here.
Calculation map
Follow the path from input to answer
01
Inputs (4)
- Sex factor used by the equation Ready
- Age Ready
- Body weight used Ready
- Serum creatinine Ready
02
Formula
Cockcroft–Gault CrCl (mL/min) = [(140 − age) × weight (kg) × sex factor] ÷ [72 × serum creatinine (mg/dL)], using 0.85 for the female factor in the traditional equation.
Bounded, transparent calculation
03
Result
- Calculate to preview the result.
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Formula, assumptions, and example
Formula: Cockcroft–Gault CrCl (mL/min) = [(140 − age) × weight (kg) × sex factor] ÷ [72 × serum creatinine (mg/dL)], using 0.85 for the female factor in the traditional equation.
Cockcroft–Gault is an adult creatinine-clearance estimate that uses age, body weight, sex factor, and serum creatinine. The page shows the equation and its limitations so the number is not mislabeled as eGFR or treated as an automatic prescription instruction.
- The equation is being used for an adult aged 18 years or older.
- Serum creatinine is stable and entered in mg/dL, not µmol/L.
- Weight is entered in kilograms and is the weight selected by the responsible local protocol.
- The traditional female factor is 0.85 and the male factor is 1.00.
- The result is an estimate of creatinine clearance and is not interchangeable with eGFR.
- Rapidly changing kidney function, pregnancy, unusual muscle mass, amputation, oedema, and extremes of body size can make a simple estimate unsuitable.
- Different medicines and guidelines may specify actual, ideal, or adjusted weight and a particular equation.
- Medication doses must be checked against the current local product information and a qualified prescriber or pharmacist.
Worked example: CrCl = ((140 − 50) × 70) ÷ (72 × 1) = 87.5 mL/min.
Displayed input contract
- Sex factor used by the equation · 2 choices
- Age · minimum 18 · maximum 120
- Body weight used · minimum 20 · maximum 300
- Serum creatinine · minimum 0.1 · maximum 20
The displayed limits are checked before the handler runs. Model-specific domain checks may also reject impossible or non-finite inputs.
Methodology: This calculator follows the WorldCalculate input, formula, precision, and boundary policy. Read the official methodology.
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Answer-first guide
How to use the Cockcroft–Gault Creatinine Clearance Calculator for a real question
Estimate adult creatinine clearance with the Cockcroft–Gault equation while clearly separating it from eGFR and medication-dosing decisions. Start with one clearly defined goal, enter values in the units shown, and keep the result attached to the assumptions below.
What this answers
This tool is useful when your question includes creatinine clearance calculator, Cockcroft Gault calculator, CrCl formula. It returns the outputs declared in the calculator contract rather than a live quote, approval, diagnosis, or professional sign-off.
What you enter
Sex factor used by the equation · Age · Body weight used · Serum creatinine. Keep the same time period, unit system, and currency wherever the form requires comparable values.
How to check it
Run the worked example first, compare its output with the page's example, then change one input at a time. This makes an unexpected result easier to trace to a unit, boundary, or assumption.
Three checks before you rely on the answer
- Match the question. Confirm that the result means the quantity you need, not a similar-sounding percentage, balance, rate, or estimate.
- Match the inputs. Use the requested units and period, and read each hint before replacing the example values with your own.
- Read the boundary. Review the assumptions and limits. The equation is being used for an adult aged 18 years or older.
Need a wider view? Browse Health Calculators or compare the related tools below. The WorldCalculate methodology explains how formulas, examples, limits, and revisions are reviewed.
How to use the Cockcroft–Gault Creatinine Clearance Calculator
- Enter Sex factor used by the equation.
- Enter Age (years).
- Enter Body weight used (kg).
- Enter Serum creatinine (mg/dL).
- Choose Calculate and read the result panel.
- Use Download PDF or Download Word to save a result sheet.
Formula
Cockcroft–Gault CrCl (mL/min) = [(140 − age) × weight (kg) × sex factor] ÷ [72 × serum creatinine (mg/dL)], using 0.85 for the female factor in the traditional equation.
Cockcroft–Gault is an adult creatinine-clearance estimate that uses age, body weight, sex factor, and serum creatinine. The page shows the equation and its limitations so the number is not mislabeled as eGFR or treated as an automatic prescription instruction.
Worked example
CrCl = ((140 − 50) × 70) ÷ (72 × 1) = 87.5 mL/min.
Assumptions and limits
- The equation is being used for an adult aged 18 years or older.
- Serum creatinine is stable and entered in mg/dL, not µmol/L.
- Weight is entered in kilograms and is the weight selected by the responsible local protocol.
- The traditional female factor is 0.85 and the male factor is 1.00.
- The result is an estimate of creatinine clearance and is not interchangeable with eGFR.
- Rapidly changing kidney function, pregnancy, unusual muscle mass, amputation, oedema, and extremes of body size can make a simple estimate unsuitable.
- Different medicines and guidelines may specify actual, ideal, or adjusted weight and a particular equation.
- Medication doses must be checked against the current local product information and a qualified prescriber or pharmacist.
Who uses this calculator?
- Students learning the Cockcroft–Gault equation
- Clinicians or pharmacists checking transparent arithmetic against a protocol
- Readers comparing creatinine clearance with other kidney-function estimates
When is it useful?
- Calculate the traditional adult Cockcroft–Gault estimate in mL/min.
- Show the effect of age, weight, creatinine, and sex factor separately.
- Teach why a creatinine-clearance estimate is not automatically an eGFR or prescription.
Context and background
How health estimates should be read
Health calculators use measurements and population-level relationships to produce screening or planning estimates. They describe the supplied model; they do not diagnose, prescribe, or replace clinical judgment.
Many familiar health formulas began as practical ways to summarize measurements. Their limits matter as much as their output because individual bodies, medications, conditions, and professional standards vary.
Research and review
How this guide was researched
Researched by Hassan ALRowaie, Founder and editorial researcher at WorldCalculate.
This guide follows the live calculator's declared inputs, formula, worked example, assumptions, validation boundaries, and source-backed methodology. The review date describes editorial review of the calculator explanation; it is not a promise that external facts or rates remain current.
Creatinine clearance estimates appear in kidney-function discussions and medication protocols, but the equation is easy to confuse with eGFR. WorldCalculate displays the traditional adult Cockcroft–Gault arithmetic and the decisions it cannot make, especially the choice of weight and the need for current clinical guidance.
What creatinine clearance means
Creatinine clearance is a way to estimate how quickly creatinine is cleared from the body. The Cockcroft–Gault equation predicts a value from age, weight, serum creatinine, and a sex factor.
It is an estimate, not a direct timed urine measurement and not a complete description of kidney health.
Cockcroft–Gault formula
The traditional form is [(140 − age) × weight × factor] ÷ (72 × serum creatinine), with 0.85 used for the female factor in the traditional equation.
Units matter: age is years, weight is kilograms, and serum creatinine is milligrams per decilitre. A creatinine value in µmol/L must be converted before use.
How to use the calculator
Choose the equation factor, enter adult age and the weight specified by the local protocol, and enter serum creatinine in mg/dL. The page shows the factor and intermediate inputs in the result.
The tool cannot decide whether actual, ideal, or adjusted body weight is appropriate for a particular medicine or person.
Worked example
For a 50-year-old man weighing 70 kg with serum creatinine of 1 mg/dL, the estimate is ((140 − 50) × 70) ÷ (72 × 1) = 87.5 mL/min.
This is a reproducible example of the formula, not a dosing recommendation.
CrCl is not eGFR
Cockcroft–Gault creatinine clearance and eGFR are different estimates with different derivations, units, indexing conventions, and intended uses. Do not rename one as the other.
When a laboratory report supplies eGFR, a medicine label or guideline may still specify another measure; follow the current protocol for the decision at hand.
Why weight choice matters
The equation includes weight, so changing from actual to ideal or adjusted weight changes the result. Obesity, oedema, low muscle mass, amputation, and very high or low body size can require a deliberate clinical choice.
Record which weight was used so another professional can audit the result.
Stable creatinine and special situations
The equation assumes creatinine is reasonably stable. Acute kidney injury, rapidly changing fluids, pregnancy, children, and unusual muscle mass can reduce the usefulness of a simple calculation.
A qualified clinician or pharmacist should choose the appropriate method when the result will change treatment.
Medication safety
A calculated CrCl should never be the only step in changing a dose. Check the current product information, local renal-dosing guideline, indication, age, interactions, and the prescriber or pharmacist’s assessment.
If someone is acutely unwell or has markedly reduced urine output, seek prompt medical attention rather than relying on an online estimate.
FAQs
Can I enter creatinine in µmol/L? Not directly; convert to mg/dL first. Is CrCl the same as eGFR? No. Which weight should I use? The weight specified by the relevant local protocol or qualified professional.
Frequently asked questions
What is the Cockcroft–Gault Creatinine Clearance Calculator?
Estimate adult creatinine clearance with the Cockcroft–Gault equation while clearly separating it from eGFR and medication-dosing decisions.
What is the formula for the Cockcroft–Gault Creatinine Clearance Calculator?
Cockcroft–Gault CrCl (mL/min) = [(140 − age) × weight (kg) × sex factor] ÷ [72 × serum creatinine (mg/dL)], using 0.85 for the female factor in the traditional equation. Cockcroft–Gault is an adult creatinine-clearance estimate that uses age, body weight, sex factor, and serum creatinine. The page shows the equation and its limitations so the number is not mislabeled as eGFR or treated as an automatic prescription instruction.
What do I need to use this calculator?
Enter Sex factor used by the equation, Age, Body weight used, Serum creatinine, then choose Calculate.
What are the limits of this calculator?
The equation is being used for an adult aged 18 years or older. Serum creatinine is stable and entered in mg/dL, not µmol/L. Weight is entered in kilograms and is the weight selected by the responsible local protocol. The traditional female factor is 0.85 and the male factor is 1.00. The result is an estimate of creatinine clearance and is not interchangeable with eGFR. Rapidly changing kidney function, pregnancy, unusual muscle mass, amputation, oedema, and extremes of body size can make a simple estimate unsuitable. Different medicines and guidelines may specify actual, ideal, or adjusted weight and a particular equation. Medication doses must be checked against the current local product information and a qualified prescriber or pharmacist.
Methodology
This calculator is part of the WorldCalculate library. Its formula, example, assumptions, input bounds, and output formatting follow the official methodology.
Use this calculator as part of a bigger plan
These WorldCalculate collections connect this tool with related questions while keeping each calculation separate and transparent.